Montreal emerges as luxury real estate hot spot Sothebys report says

first_imgVANCOUVER – Montreal is emerging as a luxury real estate “hot spot,” while Vancouver and Toronto sales should pick up this fall after somewhat sluggish times, according to a new report.Sotheby’s International Realty Canada’s rosy outlook comes despite a slew of policy changes, including some from Ottawa and a couple provincial governments designed to cool the country’s hot housing markets. However, Canada’s strong economic performance will boost the market in the coming months, says the real estate sales and marketing company.“The psychological confidence that people had in the marketplace was shaken by all of the different factors that were put in there,” said Brad Henderson, CEO of Sotheby’s International Realty Canada, of a recent drop in sales in properties of more than $1 million in Toronto.In July and August, sales of condominiums and houses over $1 million in Toronto fell 27 per cent compared to the same months the year before, according to the report. Transactions of properties over $4 million in the city fell by nearly the same amount — 28 per cent.Part of that drop came as buyers and sellers in Ontario grappled with a new 15 per cent tax on foreign buyers of properties in the Greater Golden Horseshoe Region, which includes Toronto and several nearby areas, introduced by the provincial government in late April.Ontario followed British Columbia’s footsteps in the policy. The B.C. government implemented a similar levy on foreign buyers in the Metro Vancouver area in August 2016, and the province experienced a drop in luxury property sales shortly thereafter.In Vancouver, the report says, sales of luxury real estate over $1 million dropped 23 per cent in the first half of the year compared to 2016. But, sales increased five per cent during July and August, compared to the same months last year.Sotheby’s anticipated the Toronto market would pull back not only due to the impact of its foreign buyers’ tax, but also because of a move to stricter lending rules by the federal government last year, and two recent hikes in the benchmark interest rate from the Bank of Canada.While that tempered the psychological confidence in the Toronto market, Henderson said, it boosted people’s confidence in Quebec, where the provincial government has yet to intervene.In Montreal, sales of condominiums and homes over $1 million jumped 60 per cent year over year this July and August.Sotheby’s forecasts Montreal will “emerge as a strong leader on Canada’s luxury real estate landscape this fall,” according to the report.Henderson rejects the idea that growth is primarily coming from foreign buyers who have shifted away from the newly-taxed Vancouver and Toronto markets. Though, the report cites some anecdotal evidence of “an uptick in interest from foreign buyers seeking residences.”Instead, Montreal is an attractive place to live and work, Henderson said, with the added bonus of having comparatively less expensive real estate prices.Sotheby’s also anticipates “a brisk and active” market for luxury real estate in Toronto this fall and for Vancouver to regain momentum as a strong Canadian economy is expected to boost confidence and performance in the autumn months.In Calgary, the report says “tentative optimism is set to gain ground” as the city emerges from a recession.— Follow @AleksSagan on Twitter.last_img read more

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Federal government defends thorough Northern Gateway review in court

VANCOUVER – Canada spent almost $4 million to help First Nations participate in a “thorough” and “fair” environmental assessment of the Northern Gateway pipeline project, court heard Tuesday.A lawyer for the government has asked the Federal Court of Appeal to dismiss 18 legal challenges aimed at overturning its decision to approve the $7-billion proposal from Enbridge (TSX:ENB).Lawyer Dayna Anderson said federal officials began meeting with First Nations in 2006 and revised the environmental assessment to address their concerns, most notably by adding marine shipping to the scope of the review.She added the federal government provided the $4 million to aid 46 aboriginal bands’ involvement in the process for such items as costs of travel or expert reports. The eight First Nations that launched litigation received more than $1.5 million of that funding, she said.“The Crown’s duty to consult isn’t measured in dollars and cents, and we know that, but it illustrates Canada’s attempts to ensure that meaningful participation could be had,” Anderson said.The federal cabinet approved the project in June 2014 with 209 conditions, including the creation of plans to protect caribou habitats and marine mammals. First Nations, environmental groups and a union filed court challenges, arguing the government failed to consider ecological threats or consult with aboriginal groups.Many First Nations in B.C. have not signed treaties and have unresolved land claims. But they argue a landmark Supreme Court of Canada decision that gave the Tsilhqot’in title to their territories means the government must not only consult with them, but seek their consent.Anderson disputed that interpretation, stating the government must only seek consent from nations that have court-recognized title. The Crown chose not to debate First Nations’ title or governance rights during consultations on the Northern Gateway pipeline, referring those issues to the treaty process.Lawyer Jan Brongers said the federal review panel heard both oral and written evidence from indigenous groups and determined the pipeline would not have significant adverse effects on traditional use of their lands.He said the panel concluded the 209 conditions would mitigate nearly all the ecological risks, apart from threats to certain woodland populations of grizzly bears and caribou, which were found to be “justified” given the expected economic benefits of the pipeline.“It is our firm position that the order-in-council, which is the culmination of a lengthy, thorough and fair environmental assessment process, which included honourable consultation with the impacted First Nations, strongly deserves to be left in place,” he said.Brongers said previous rulings have set a high standard for a court to toss a decision made by a democratically elected cabinet on a resource project. The judges must find the decision broke the law or had no reasonable basis in fact, he said.The 1,177-kilometre double pipeline would ship diluted bitumen from Alberta’s oilsands to a terminal on British Columbia’s north coast, boosting Canada’s gross domestic product by an estimated $300 billion over 30 years.Northern Gateway and the B.C. government will state their cases later this week, before the hearing is expected to wrap up Thursday.— Follow @ellekane on Twitter. The Douglas Channel, the proposed shipping route for oil tanker ships in the Enbridge Northern Gateway Project, just south of Kitmat, B.C., is pictured on Jan. 10, 2012. The Canadian government is asking the Federal Court of Appeal to uphold its controversial decision to approve the Northern Gateway pipeline project. THE CANADIAN PRESS/Darryl Dyck by Laura Kane, The Canadian Press Posted Oct 6, 2015 12:37 pm MDT Last Updated Oct 7, 2015 at 3:40 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Federal government defends ‘thorough’ Northern Gateway review in court read more

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Womens volleyball Ohio State falls to Michigan for second time this season

Freshman defensive specialist Hannah Gruensfelder (7) makes a dig for the ball at the Ohio State women’s volleyball game against Michigan at St. John’s Arena in Columbus, Ohio on Oct. 22. The Buckeyes lost the match 3-1. Credit: Maggie Jones | For The LanternAs 4,583 fans gathered in St. John Arena Sunday afternoon, both Ohio State and Michigan felt eyes on them as the two rivals clashed for the second time this season. The Ohio State women’s volleyball team (11-10, 4-6 Big Ten) was unable to enact its revenge on Michigan (14-8, 4-6 Big Ten) for the Wolverines’ win earlier this season, again losing the match 3-1.“I think that the effort was there on our part, but I don’t think that we had necessarily the right attitude or energy level,” freshman defensive specialist Hannah Gruensfelder said. The Buckeyes put together their strongest performance in the third set when they avoided the three-set sweep. With seven ties, six lead changes and consecutive kills by setter Taylor Hughes and outside hitters Bia Franklin and Ashley Wenz, the Buckeyes came back from a 24-21 deficit to tie the Wolverines 24-24 after trailing the entire set. Ohio State completed the comeback and won the set 28-26.The Buckeyes took a 22-20 lead in the second set with a 7-0 run, forcing the Wolverines to call a timeout. But Ohio State was unable to continue its momentum as Michigan quickly regained the lead and won the set 25-22.The first set went back-and-forth with 15 ties and four lead changes. The see-saw set did not tilt in the Buckeyes’ favor in the end, however, despite 12 digs, 10 assists and three blocks, as Michigan’s junior outside hitter Carly Skjodt notched two consecutive kills to secure the opening set for the Wolverines 25-23.Twelve blocks from Ohio State’s defensive line proved insufficient in the fourth set as the Buckeyes quickly found themselves trailing in the set. After calling a timeout down 20-15, the Buckeyes proceeded to lose the set 25-19 and the match 3-1.Senior outside hitter Luisa Schirmer thought the Buckeyes were aggressive, but the Wolverines played harder.“Michigan is a great team and I think they attacked us really well and stressed us out on our serving,” Schirmer said. “Like we always say in the Big Ten, today maybe wasn’t our day and we come back and reevaluate and come out for the next game.”Gruensfelder said her team could have pushed harder and played with more energy playing at home in front of such a large crowd.“[The Wolverines] were hitting pretty hard and they were definitely bringing their A-game,” Gruensfelder said. “We were all just kind of complacent with what was going on at the time, but we needed to do more. Just having that drive throughout the entire game is something that we can really work on.”Moving forward, Schirmer and Gruensfelder believe the key to finding more success will come down to improving shot selection when in bad situations while also creating new opportunities for themselves.“I think, in a sense, extending rallies when the ball isn’t in a great spot and letting the other team make the error and kind of play extenders at a point until we get the good set to make the kill,” Schirmer said. “I’d say that’s definitely something we’re working on in the gym.”Ohio State will play Purdue at 7 p.m. Friday and Indiana at 8 p.m. Saturday. Both games will take place at St. John Arena. read more

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I Faced Off Against The Worlds Best Chess Player You Will Totally

I had the black pieces, meaning that Carlsen went first. He opened with d4, moving his queen’s pawn forward two squares. I did the same. He then moved a pawn to c4, employing what’s called the queen’s gambit. White seemingly offers a free pawn to black in exchange for what promises to be a fruitful attack. I declined, and we ended up in an opening called the queen’s gambit declined, exchange variation.I lasted 25 more moves. It was over well before that. If you absolutely must, you can see the full game below.In retrospect, I blundered — unbeknownst to me at the time — on my 12th, 13th and 17th moves. Others too, I’m sure.This was always going to happen. But as I sat shroudless, Carlsen did break my heart. By move 12, he’d pushed a pawn down his right flank, which caused me all sorts of problems, and my king was the equivalent of a sitting duck on the opening day of hunting season. But my own pawn, my little pawn that could, was on the march. My pawn made it two squares from the end of the board, where it could become a queen. And it would soon defend my extant queen, which on the next move fled down the board to put Carlsen in check — I put Magnus Carlsen in check! I confess that for precisely 1.5 seconds I thought, “I am going to fucking win.”Carlsen then easily defended, parried … and destroyed me.But I fought!My editor insisted that this story “somehow work in data,” so I will now add a patina of empirical humiliation to this solid bronze piece of embarrassment. I recorded Carlsen’s and my moves and later ran them through the powerful computer chess engine Stockfish, which evaluates every position and provides an estimate of who’s more likely to win. UNITED NATIONS — I nearly deleted the email. I’m not accustomed to receiving genuine correspondence from a counsellor with the permanent mission of Norway to the United Nations, so I almost filed it away with that day’s other press releases, including an exciting interview opportunity with the former CEO of the parent company of Hardee’s. But a name in the middle of the email’s first paragraph just caught my eye: Magnus Carlsen.And that’s how I found myself in Conference Room 8 in the headquarters of the U.N. last week playing chess against maybe the best chess player who has ever lived — and who also happens to be, at age 27, the reigning world champion and at the height of his awesome powers.My basic problem: I had very little idea what I was doing. A secondary, but increasingly dire, problem was that I was nervously and uncontrollably shaking. A frantic Google search told me that that was probably due to an acute and supposedly beneficial stress response, also known as fight or flight.Fight or flight? For me, chess is a cultural and aesthetic experience — and one that I’m lucky enough to get to write about sometimes. It is not, typically, a competitive one, in the sense that I’m just not very good. I’ve always held grandmasters in high regard, and I do even more so now. I’ve witnessed an Ali knockout firsthand.Carlsen will face an American of somewhat greater chess note than I — Fabiano Caruana, the world No. 2 — in a match in November to defend his world championship crown. Just two players, alone and battling in a game without luck and with nowhere to hide. I asked Carlsen if he considered his game against me to be part of his official world championship preparation.“Um, no,” he said. In his crowning achievement of the game, the author, top left, makes a move that causes the world’s best chess player, right, to think carefully about his next move. The game ended in the author’s defeat soon after. Svenn Richard Andersen To my nervously trembling chagrin, they’d set up my chess board correctly and in the traditional fashion: I had only the one queen and the two rooks and so forth, and somehow it was deemed appropriate that Carlsen start with the identical and equal number of pieces. A grandmaster buddy of mine texted me before the game, “Make sure your pieces are defended.” It certainly sounded simple enough. My aunt wrote on Facebook, “I hope Oliver wins!” Other well-wishers wished me “good luck.”Thanks, but what luck? Chess is stripped of that frivolity; it’s the canonical no-chance, perfect information game. That nakedness is why boxing is a good analogy to chess: two people battling in a confined space with nothing, not a shroud of randomness or the fog of war, to hide behind. I once beat the Scrabble national champion (in Scrabble, not chess), but that was only because a) I sort of knew what I was doing and b) there is luck in that game that I could hide behind. I got lucky. Awaiting the world chess champion, I harbored no such idiotic delusions as I sat at an enormous horseshoe table, fretting and adjusting the pieces. Carlsen was about to do to my psyche what Mike Tyson would’ve done to my face. There was no escape.There were 15 of us awaiting that fate — the mayor of Oslo, the Afghan ambassador to the U.N., a legal adviser with the Maldives mission, me, etc. The usual suspects.The event was a “clock simul,” short for “simultaneous exhibition with clocks,” in which each of us “challengers” sat at our own boards while Carlsen, the “exhibitor,” darted around the room, rarely taking more than a few seconds to make any move before moving on to his next victim. We each had 30 minutes to make all our moves, but Carlsen’s clocks constantly ticked away at every board, putting him at a nominal disadvantage.Here’s a technical diagram of the Carlsen-Roeder game at the exact moment when it really went off the rails: read more

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The Raptors Bench Is Destroying The NBA

The Toronto Raptors are on top of the Eastern Conference for all sorts of reasons, and one of them is their bench. In the video above, we break down what’s made the Raptors’ reserves so good, and why the team shines when its stars hit the pine.

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Athletic department centennial celebration delayed for Obama

The Ohio State athletic department was prepared to kick off its centennial celebration commemorating 100 years as a department and as a member of the Big Ten conference this week. That was until President Barack Obama announced his plans to visit the OSU campus on Saturday. The athletic department’s yearlong celebration was slated to begin at the Buckeye baseball and softball home games. Fan festivities were planned, with several baseball and softball alumni scheduled to attend. In an email to The Lantern, OSU athletic director Gene Smith said he and several members of the committee involved in the celebration planning decided that it was best to postpone the events to minimize traffic concerns in the area around the Schottenstein Center. “The presidential visit is complex with security,” Smith said. “Our priority is to ensure the games themselves go smoothly, softball and baseball, and make it as easy as possible for the fans to enjoy the contests our student-athletes compete in.” Janine Oman, assistant athletic director for sport performance and head of the committee overseeing the centennial celebration, said everything was set to begin this week, but the unexpected circumstances forced a change in the schedule of events. “We were originally planning on doing kickoff games this weekend,” Oman said. “However, the president is coming right at the same time.” While the games will still take place Saturday, the fan activities will be rescheduled due to the arrival of the president and his subsequent speech Saturday morning at the Schottenstein Center. Oman said the first kickoff games will take place Sept. 21 at the field hockey and women’s volleyball games. Austin Stewart, a first-year in international studies, said he was unaware the athletic department was planning a celebration set to begin this week. With the president coming though, he said it’s probably a good idea that it has been moved back. “The president is gonna take a lot of attention away … that would be with the 100-year celebration,” Stewart said. While he admitted he is not really a fan of the president, Stewart said he would rather go see him speak Saturday than attend the anniversary festivities because of the rare experience it presents. “It’s the president of the United States coming to campus. That doesn’t really happen all that often,” Stewart said. “I would probably rather go see him just because that’s a once-in-a-lifetime opportunity.” Obama will speak at the Schottenstein Center Saturday at 1:25 p.m., with the doors opening at 10:30 a.m. First Lady Michelle Obama will join her husband in support of his campaign. The public event on OSU’s campus is the official beginning of the 2012 election, and Obama has a rally planned at Virginia Commonwealth University later on Saturday. This rally marks the second visit Obama has made to OSU’s campus in about two months. Republican candidate Mitt Romney has also been in central Ohio in the past week. Romney spoke at Otterbein College last Thursday about the economy and his plan to bring the nation back to a world leader. read more

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Ohio State mens soccer teams losing streak at 3 with 2 road

Then-sophomore defender Austin Bergstrom (25) kicks the ball during a game against Michigan in the first round of the Big Ten Tournament on Nov. 9 at Jesse Owens Memorial Stadium. OSU won, 1-0. Credit: Lantern File PhotoThe beginning of Ohio State men’s soccer team’s first road trip this season turned sour after a pair of losses to No. 17 University of Maryland, Baltimore County (3-0-1) and Navy (2-1-1) over the weekend.After Friday’s loss to the ranked UMBC in Baltimore, the Buckeyes stayed in the state of Maryland but were blown out by a score of 3-0 against Navy on Sunday in Annapolis.OSU had a good chance to score in the 29th minute, but OSU sophomore forward Marcus McCrary’s shot was deflected off the side of the net from six yards out.Navy sophomore forward Aubrey Jones scored a 10-yard goal in the 36th minute of the game to give the Midshipmen their first point on the board.The Buckeyes had another chance to score in the 60th minute when McCrary passed the ball to OSU junior forward Danny Jensen, who then launched the ball toward the net. However, Navy senior goalkeeper Jackson Morgan denied Jensen’s shot to maintain the one-goal advantage.OSU continued to battle against the home squad in the 19th minute of regulation, but the Midshipmen managed to put two more points on the board giving the team a final score of 3-0.Overall, Navy held a 5-3 advantage in the corners over the Buckeyes.Despite a better performance two nights before at UMBC, the Buckeyes still opened the weekend the same way they closed it: scoreless.The Buckeyes held a 9-0 advantage in the corners and a 5-2 lead in shots in the first half of the game, but were unable to get anything into the net.OSU senior midfielder Kyle Culbertson attempted a shot from the corner in the seventh minute, but his attempt was blocked, taking away the opportunity for a Buckeye point. OSU senior midfielder and co-captain Zach Mason went for the first shot on goal for OSU from the corner in the 10th minute, but it was saved by UMBC sophomore goalkeeper Billy Heavner.The Buckeyes had two back-to-back corner kicks finishing the first half, but they could not execute, leaving the game scoreless at the break.Midway through the second half, UMBC senior forward Darius Madison scored a goal from 14 yards out in the 59th minute of the game, giving the Retrievers a 1-0 lead over the Buckeyes.OSU continued to fight back for a chance to tie the game, but continued to be unable to score.McCrary came close to scoring a goal in the 68th minute when he launched the ball 12 yards into the goal. However, Heavner saved McCrary’s kick.With one final attempt, OSU senior defender and co-captain Liam Doyle was given the opportunity of a free kick in the 89th minute, but couldn’t make a connection between the ball and the net, giving the team a 1-0 loss against UMBC.OSU senior goalkeeper Chris Froschauer now falls 1-3 on the year, stopping just five of nine shots on goal over the weekend.The Buckeyes are next scheduled to open Big Ten play on the road against Northwestern on Friday in Bridgeview, Illinois, at 8 p.m. read more

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Havilah – PFS status and timing for Kalkaroo coppergold project

first_imgHavilah Resources Ltd has been advised that the Kalkaroo PFS is substantially complete and that RPM Global plans to deliver a draft of the PFS to its client Wanbao Mining Ltd by the middle of January 2018. The document was to be delivered by the end of December 2017, but there was a minor delay due to late receipt of certain metallurgical test results. Havilah has used this period to do further reviews of PFS data provided to date and to perform some additional analysis and trade-off studies of certain aspects of the project. As planned, there will be a period of consultation following delivery of the PFS document and Havilah technical personnel will meet with Wanbao in Beijing for a joint review and evaluation of the PFS results later this month. Part of the objective would be to ensure the PFS properly reflects the value, potential upside, and opportunities related to the Kalkaroo copper-gold project.Following this period of consultation between Havilah and Wanbao and upon receipt of RPM Global’s final PFS document, Havilah will be in a position to make a further announcement regarding the PFS outcomes, which is expected to be before the end of the first quarter of 2018. This will include a Probable Ore Reserve, expected capital cost of the project and an NPV for the project.Under the non-binding memorandum of understanding, Wanbao has two months after delivery of the final PFS document to make an investment participation decision.Kalkaroo in South Australia is one of the largest undeveloped copper-gold projects in the country, containing JORC Measured, Indicated and Inferred resources of 232 Mt of copper and gold for over 1.1 Mt of copper and 3.3 Moz of gold. The project is capable of producing high quality copper-gold concentrates plus copper metal (as native copper) and gold dore. To develop the Kalkaroo project at an optimum mining and throughput rate requires a major capital investment and considerable operational expertise.last_img read more

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Behind the scenes as the Capuchin Day Centre prepares to feed 500

first_imgSix days a week, the centre serves breakfast and dinner to hundreds of people and provides food packages to over a thousand a week.Brother Kevin Crowley, who established the service back in the 60s, told TheJournal.ie that around 250 people come for breakfast every morning and staff and volunteers serve dinner to between 450 and 500 every afternoon.Many of the people attending the centre do so on a regular basis and those providing the service offer more than just a hot meal. Warmth and dignity – two things severely lacking in the everyday lives of many of the people who avail of the service – greet them at the door. As Brother Kevin explains, no questions are asked and nothing is expected in return.(Video: TheJournal.ie/YouTube)“What is amazing is the numbers of families that come here and it’s very sad to see young children having to come to a place like this but our main concern here is for the welfare of the people who avail of the centre,” Crowley said.The centre has a separate section for families with toys for children to play with and pictures on the wall to make it colourful and welcoming:Each year, the demand for the services the Capuchin Day Centre provides has been increasing and has doubled since 2008, though the level of funding it receives from the government has remained the same, Crowley told TheJournal.ie in an interview.The poor and the marginalised are the people who can and always will be more or less forgotten by society.Today they were not forgotten and when the doors opened at 1pm, the normal buffet set-up was abandoned with volunteers serving the 500 diners at their tables like in a restaurant to make the day extra special and a live band providing entertainment.Crowley said none of this would be possible without the “kindness and generosity” of the public who have continued to donate to the centre every year, all throughout the recession.“We have never run short of food and we never went short of money,” he added. “The people are fantastic”.All images and video © Michelle Hennessy/TheJournal.ie.Read: ‘I’m the CEO of the Capuchin Day Centre and my salary is nil’> TODAY THE CAPUCHIN Day Centre held its annual festive feast, serving up a full three course meal to some 500 people.This is the day that all the staff, volunteers and the people who attend the homeless centre look forward to most. Homemade soup, roast ham and turkey and a selection of delectable deserts were on the menu and the centre’s head chef Ann has been working flat out to make sure everything would run smoothly.Over the last two days, she and the other staff and volunteers working in the kitchen have been up from early in the morning so everything would be ready to go for the gala today.When we visited yesterday, the turkeys and hams were cooked and sliced:The potato croquettes were breaded and ready to be fried:There were 500 trifles chilling in the fridge:And just as much ice cream in the freezer…There were also a few sweets to go along with the after dinner tea and coffee:last_img read more

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Legislation aims to inspire confidence in schools enrolment policies

first_imgSCHOOLS COULD BE required to include an “explicit statement” in their enrolment policy to avoid discrimination.It would be included in the Education (Admissions to Schools) Bill 2014, which Minister for Education Ruairi Quinn today received approval for drafting.The legislation will target schools that are over-subscribed, meaning that some pupils will not be accepted.The Department said the legislation will have a “marginal impact” as this constitutes around 20 per cent of schools.If enacted, a schools would be required to include a clause in their admissions policy stating that it would not discrimination “against an applicant for admission on the grounds of disability, special education needs, sexual orientation, family status, membership of the traveller community or race”.“Parent-friendly”The General Scheme of the Bill, published last September, aimed to bring “a parent-friendly, equitable and consistent framework to regulate school admissions policy” for Ireland’s 4,000 primary and post-primary schools.“The aim of this new Bill is to inspire the same levels of confidence in the enrolment of pupils in schools as the CAO system inspires for those who are applying for limited places in third level colleges,” Minister Quinn said today.The Department of Education also clarified that this legislation would enable the National Council for Special Education and the Child and Family Agency to “designate a place for a child for whom no school place is available”.Previously: Schools face ban on charging admission fees or interviewing parents on enrolment >last_img read more

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What is an accelerated processing unit APU

first_imgEarlier this week AMD had some big news and the term “APU” was tossed around a lot. This surely had a lot of people wondering what the heck an APU is and how it differs from a central processing unit (CPU).The video above shows how an APU works by explaining the flow of data through the components involved. It also compares how a CPU works to how an APU does things. It’s helpful enough, but if you already know some of the basic terms (CPU, GPU, etc.) then Wikipedia’s definition might be better:An APU integrates a CPU and a GPU on the same die thus improving data transfer rates between these components while reducing power consumption. APUs can also include video processing and other application-specific accelerators. Examples: Intel’s Sandy Bridge, AMD Fusion and NVIDIA’s Project “Denver” Make more sense now? An APU is the combination of a CPU (generally a multi-core one), a graphics processing unit, and then some way to get them to play together nicely.Why do this in the first place? Because it turns out that GPUs are good at things besides graphics, so the CPU can offload computing tasks to them. To optimize this cooperation bottlenecks between the CPU and the GPU had to be removed, the result being the APU!via InsideHPClast_img read more

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La poule était là avant loeuf arguments scientifiques à lappui

first_imgLa poule était là avant l’oeuf, arguments scientifiques à l’appuiRoyaume-Uni – Qui de la poule ou de l’œuf est arrivé le premier ? Si la question restait sans réponse depuis des siècles, des scientifiques des universités de Sheffield et Warwick pensent aujourd’hui être capables d’y répondre. Selon les chercheurs, c’est la poule qui serait arrivée la première. Ils ont en effet découvert que la formation de la coquille d’œuf dépend d’une protéine trouvée uniquement à l’intérieur des ovaires de la poule. Le raisonnement est simple : sans poule, pas d’ovaires ; sans ovaires, pas de protéine ; sans cette protéine, pas de coquille et sans coquille, pas d’œuf. Ou autrement dit, un œuf ne peut voir le jour qu’à l’intérieur d’une poule. À lire aussiAlpha-foeto-protéine : définition, rôle, comment analyser les résultats ?La protéine en question, appelée ovocledidine-17, ou OC-17, agit comme un catalyseur accélérant le développement de la coquille, indispensable pour abriter le futur poussin et lui permettre de se développer. Grâce au super-ordinateur HECToR basé à Édimbourg, les chercheurs ont mis en évidence que l’OC-17 était cruciale dans les premières étapes de la cristallisation de la coquille.Pour le Dr. Colin Freeman de l’université de Sheffield : “On a longtemps suspecté l’œuf d’être arrivé le premier mais maintenant, nous avons la preuve scientifique que c’est en fait la poule qui était là avant.” Le 17 juillet 2010 à 12:22 • Emmanuel Perrinlast_img read more

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Fabian Schar ready for tough Premier League test

first_imgNewcastle new signing Fabian Schar is looking forward to proving himself in the “best league in the world,” adding that the desire to play under Benitez was the driving force behind his Newcastle signing.The Switzerland international is now on a three-year deal with Newcastle from Deportivo La Coruna for £3m. He is also excited by the prospect of testing himself in the upcoming Premier League.Speaking to Sky Sports Schar said:“The Premier League is the best league in the world, you have so many good players and many good teams. Almost everybody can beat everybody so that is what I am looking forward to.“With the great stadiums and all the fans, it’s going to be fantastic next season. I’m really happy to be here. England is the best league in the world.Jose Mourinho is sold on Lampard succeeding at Chelsea Tomás Pavel Ibarra Meda – September 14, 2019 Jose Mourinho wanted to give his two cents on Frank Lampard’s odds as the new Chelsea FC manager, he thinks he will succeed.There really…“I need some training and some more pre-season because the season is coming quick, and I have to be ready in maybe just two weeks. I’m really looking forward to it.“I have had maybe two or three training sessions with team-mates, and one game, so I need some time but what I have seen is that we have a good team and quality in the squad.”He added:“He (Benitez) gave me a good feeling, he’s a big coach with a lot of experience, and Newcastle is a big team so it seemed to me to be perfect. I’m really happy.“I am a defender and I know how to defend. My first job is to keep the score to zero. My quality is to help in the build-up with good long passes, this is my strength and why Rafa Benitez called for me.”last_img read more

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Plane crash on Sunday off Grand Bahama

first_imgFacebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppFrom the Bahamas – A plane crash on Sunday off Grand Bahama island has claimed the life of the four people aboard the Cirrus SR22. Reports are that the single engine aircraft crashed just minutes after take-off from the Grand Bahama airport and was totally destroyed, broken in pieces. Police are withholding identities, but there is an indication the four Americans are linked to Indiana. The plane crashed about seven miles north of the Freeport Control tower. According to an online news source, the four passengers, two males and two females were said to be on a sightseeing trip when the pilot radioed the tower that the plane had developed engine problems. Related Items:last_img read more

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Apology from Gov Walker over historical trauma highlights day one of annual

first_imgGovernor Bill Walker gets emotional addressing the resignation of his lt gov during his address during AFN at the Dena’ina Conference Center in Anchorage (Photo by Zachariah Hughes, Alaska Public Media – Anchorage)The first day of the Alaska Federation of Natives Convention in Anchorage saw protests and a high-level apology.Listen nowValerie Nurr’araaluk Davidson was already set to be the keynote speaker. But the speech took on even more importance after the surprise announcement Tuesday that she had been sworn in as Lieutenant Governor amid Byron Mallott’s sudden resignation over “inappropriate comments” — something Davidson referred to in her speech.“Let’s acknowledge where we are. Just two days ago our world shifted,” Davidson said. “I want you to know, Alaskans deserve the highest standard of conduct from their elected officials. Respect for women and the dignity of all Alaskans is our responsibility.”Valerie Nurr’araaluk Davidson giving her keynote address at the Dena’ina Convention Center during AFN (Photo: Zachariah Hughes – Alaska Public Media)The address was broad and personal, touching on the administration’s expansion of Medicaid, Davidson’s own struggles with childhood trauma, and the importance of the tribal compact the state announced last year. Over and over again, Davidson said the current administration’s policies have significantly elevated the role of Alaska Natives in guiding state policy.“We invited more people to the conversation and recognized that listening is more important than litigation,” Davidson said.Soon after came an address by Walker himself. He, too, referred to the week’s resignation without calling Mallott a brother and “soul mate” who had taken responsibility for a mistake. Though Walker never overtly focused on the dynamics of his re-election campaign, which currently favor his Republican opponent, he did allude to it briefly.“This may be the last time I address you formally. I recognize that,” Walker said.With that, Walker primed the audience for a big announcement, and for a minute it seemed like the room was holding its breath. But it wasn’t a campaign revelation; instead, it was a formal apology to Alaska Natives for the wrongs they have endured from the State.“As the 11th governor of the state of Alaska, I apologize to you, Alaska’s first people, for the wrongs that you have endured for generations,” Walker said. “For being forced into boarding schools, I apologize. For (being) forced to abandon your Native language and adopt a foreign one, I apologize. For erasing your history, I apologize. For the generational and historical trauma you have suffered, I apologize. This apology is long overdue. It is but one step in hundreds more to go on this journey towards truth, reconciliation and healing.”It was the first such apology to Alaska Natives on past state policies from a sitting governor, according to a Walker aid.Walker also thanked the federation for embracing him during his term as governor.Two blocks away from the convention stage, demonstrators gathered for a rally focused on defending indigenous women and protecting the environment.Quannah Chasing Horse Potts called for an end to violence.Princess Daazhraii Johnson speaking during a rally by Defend the Sacred AK outside the Performing Art Center not far from AFN (Photo: Zachariah Hughes – Alaska Public Media, Anchorage)“For far too long, women, our indigenous women, our lands and our waters, have been traumatized and victimized,” Potts said.The rally was organized by Defend the Sacred AK, and brought together a patchwork of groups focused on wildlife conservation, subsistence rights, as well as domestic violence and sexual assault prevention. Well over a hundred people gathered outside the Performing Arts Center in downtown Anchorage.AFN continues through Saturday, with remarks from gubernatorial candidates and Alaska’s congressional delegation in the days ahead.Correction: an earlier caption misidentified Princess Daazhraii Johnson.This story contained contributions from Zachariah Hughes, Abbey Collins and Andrew Kitchenman.last_img read more

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After Santa Fe Shooting Gov Greg Abbott Sees A West Texas Mental

first_img Share Michael Ciaglo/Houston Chronicle/Via NPRPeople embrace outside the Alamo Gym where students and parents wait to reunite. Michael Ciaglo/Houston Chronicle/Via NPRA Lubbock-based program seeing success helping prevent at-risk students from committing violent acts is getting more attention after Gov. Greg Abbott touted it as a potential statewide model to reduce school shootings the day after a student allegedly shot 10 people to death at his a southeast Texas high school.The Telemedicine Wellness, Intervention, Triage, and Referral Project at the Texas Tech University Health Sciences Center works to identify junior high and high school students most at risk for committing violence in schools and intervene before it happens.At Santa Fe High School on Friday, police said 17-year-old junior Dimitrios Pagourtzis, armed with his father’s legally-owned shotgun and .38 revolver, killed eight students and two teachers and wounded 10 others. Pagourtzis, who had written about his plans in his journal but otherwise showed no obvious danger signs according to Abbott, has been charged with capital murder and remains in Galveston County Jail without bond, the school district said.Abbott alluded to Tech’s program in a Friday tweet, saying “we want to use it across the state.”But could it identify, and stop, someone like the alleged Santa Fe shooter?Billy Philips, executive vice president for rural and community health at Tech’s Health Sciences Center, said he “was a bit surprised” to hear Abbott mention the program, which he said has seen success but is still being refined and perfected.Philips said the project has found students at West Texas schools possessing notes, maps, threats and other evidence that they may have been planning a mass shooting. He said the screenings have helped avert violent incidents and got students the help they needed.“The aim of it is really to provide just one more tool to be sure that our schools are safe,” Philips said. “To make sure that our kids have the opportunity to not worry while they’re in school, to create a peace about it so they can learn and grown and share ideas … things we all did when we were in school.”   The program launched in 2014, in response to a pair of mass shootings in 2012: A theater shooting in Aurora, Colorado that killed 12 people and injured 70 others and the Sandy Hook Elementary School shooting in Newtown, Conn. that left 20 children and six adult staff members dead.The Criminal Justice Division of Abbott’s office funded the program with a $565,000 grant.Through the program, at-risk students at 10 West Texas school districts who show aggressive or harmful behavior are identified and then screened for potential psychiatric services. Parents have to consent each step of the way. Students first receive two psychiatry sessions at school — in which they use laptops to video conference with a child adolescent psychiatrist working remotely — and additional psychiatric services are provided through the center’s clinic.Since its launch, more than 400 students have been referred to the program, with 200 getting screened for anxiety, depression, loneliness, isolation — and whether they’re prone to violence or violent thoughts. Those screenings can lead to psychiatric appointments and sometimes immediate hospitalizations and arrests for planning violent incidents like shootings, according to an April 30 brief that Tech’s Health Sciences Center published about the program.In four years, the program has had 25 students removed from school, 44 placed in alternative schools and 38 sent to a hospital.The project also measures success through changes in grades, truancy referrals and discipline referrals. So far,  Philips said, the program has seen a 37 percent drop in referrals for students who received services.He said the program also helps the targeted schools amid a statewide shortage of mental health professionals. Philips said before the program, students would sometimes have to wait weeks to get an appointment to see a psychiatrist. Using telemedicine, “we can get those links in moments and those moments can be critical in some situations,” he said.Philips said the program is looking to expand into five more school districts.“We’ve got about a third of our kids in schools these days who are troubled by some form of mental illness either directly or because they live in a home environment where someone has trouble,” Philips said. “The services need to be there for them, the people need to be there that are trained to help with mental health issues. This is one approach that we use in schools that seems to be very effective.”  last_img read more

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Texas Secretary Of State David Whitley Departs As Legislative Session Ends

first_img Share Miguel Gutierrez Jr. / The Texas TribuneSecretary of State David Whitley departs after his office flagged about 98,000 voters for citizenship checks — 25,000 of them in error and many more likely because they were naturalized citizens.The ill-fated tenure of Texas Secretary of State David Whitley has come to an end.The Texas Senate gaveled out Monday without confirming the state’s top election official, who served for less than half a year and whose tenure was mired in controversy over a failed attempt to scour the voter rolls for noncitizens — a review that questioned the citizenship of thousands of legitimate voters.But minutes before that happened, the Austin American-Statesman reported that Whitley had submitted his resignation. The secretary of state is constitutionally required to leave office immediately if the Senate goes through an entire legislative session without confirming him.His departure is an unusual end; gubernatorial appointees typically sail through the Senate.Whitley, a former top aide to Gov. Greg Abbott, departs after his office flagged about 98,000 voters for citizenship checks — 25,000 of them in error and many more likely because they were naturalized citizens.First appointed in mid-December, Whitley oversaw the botched review that pulled the state into three federal lawsuits, prompted a congressional investigation over concerns of voting rights violations and frayed the relationship between the state’s election office and the local officials it depends on to run elections.In the end, the review caused more problems for the state than it solved, fueling doubts about the unsupported claims of rampant voter fraud it sought to address. And it stoked deep partisan scars in a Legislature with a long history of suppressing the rights of voters of color.Senate Republicans were short on votes to confirm Whitley without any Democratic support. Although they are a political minority in the chamber, the Democrats’ block held firm throughout the legislative session in impeding the confirmation of a chief elections officer who needed two-thirds support of the Senate to keep his job.All 12 Democratic senators went on the record as “nays” on Whitley’s confirmation in February, citing concerns over the fear the review had caused among legitimate voters who were not born in the U.S. and who are more likely to be people of color. During the review, some of those individuals received letters demanding they prove their citizenship to avoid being kicked off the rolls.“The reality is that Democrats showed solidarity on that issue because of Whitley’s position of voter suppression,” state Sen. Royce West, D-Dallas, told reporters after the Senate adjourned. “That was the issue.“It was not that he was not a good person — he seemed like he was a great person — but not the secretary of state, especially concerning the issues the secretary of state has to deal with as it relates to voting.”Throughout the debacle, Whitley and other state officials repeatedly defended the review as a legitimate effort to improve the integrity of the state’s voter rolls. But it was riddled with errors.After tagging the roughly 98,000 voters for review, the secretary of state’s office quietly acknowledged almost a quarter of the names were mistakenly included. Local election officials said they were able to identify more than 1,000 other naturalized citizens on their lists before a federal judge halted their reviews. Weeks later, the secretary of state inadvertently sent additional names for review to certain counties because of a technical error a spokesman blamed on a vendor.State officials eventually agreed to give up on the review as part of a legal settlement to shut down the litigation the state faced. That left taxpayers on the hook for $450,000 in costs and attorney fees for the lawyers of the naturalized citizens and civil rights groups that alleged the review was unconstitutional and violated federal protections for voters of color. A federal judge appeared to have similar misgivings in late February when he put the review on hold over concerns that “perfectly legal naturalized Americans” were targeted in ways those born in the country were not.Despite the settlement, Whitley’s confirmation was seemingly too far gone. Last-ditch efforts to sway Democratic senators proved unsuccessful.Still, Abbott appeared to hold out hope on the nomination through the final hours.“We’ll need to wait and see how today turns out,” Abbott told reporters at an unrelated news conference Monday morning in Austin, less than an hour before the Senate was set to meet for the last time this session.Asked if he thought the Senate should have fought harder to confirm Whitley, Abbott said he thought the Senate “fought hard, and we’ll see how things turn out.”It’s unclear how quickly Abbott will move to fill Whitley’s post. The constitution states the governor shall “without delay” make another nomination to fill the vacant post. The governor’s office did not immediately respond to a request for comment Monday.Patrick Svitek contributed to this report. This piece was originally published on The Texas Tribune, a nonprofit, nonpartisan media organization that informs Texans — and engages with them — about public policy, politics, government and statewide issues. Disclosure: The Texas secretary of state’s office has been a financial supporter of The Texas Tribune, a nonprofit, nonpartisan news organization that is funded in part by donations from members, foundations and corporate sponsors. Financial supporters play no role in the Tribune’s journalism. Find a complete list of them here.last_img read more

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Mass Effect 2 Free On PC Through Origin For A Limited Time

first_imgMass Effect 2 was officially announced back in March of 2009 and released a year later for Xbox 360 and PC. In its first week of release, Mass Effect 2 sold-in over two million copies globally. The game received numerous awards and perfect scores from various media outlets and was later released on PS3 as well.The Mass Effect trilogy is an epic science fiction adventure set in a vast universe filled with dangerous alien life and mysterious, uncharted planets. In Mass Effect 2, players will once again step into the role of the heroic Commander Shepard, commanding their crew of some of the most dangerous operatives from across the galaxy on a mission so challenging that it’s potentially suicidal. Featuring intense shooter action, a rich futuristic storyline, space exploration and emotionally engaging character interaction, the game delivers an unparalleled cinematic experience.“Mass Effect 2 is poised to be one of the biggest games of 2010. We could not be more proud of the game’s universal acclaim and early commercial success”, said Dr. Ray Muzyka, co-founder, BioWare and Group General Manager of the RPG/MMO Group of EA following the game’s release.  “Rich, immersive worlds, compelling characters and stories, and intense action are some of the hallmarks of BioWare games, and Mass Effect 2 truly raises the bar in every area. I’m incredibly proud of our team, who worked passionately to deliver a very high-quality game for our fans. This epic sequel in the stunning Mass Effect universe is an extraordinary accomplishment, one which we can’t wait to get into the hands of a worldwide audience!”As said, PC players can now get Mass Effect 2 on the house via Origin. PC players can now get Mass Effect 2 free through EA’s Origin for a limited time only.Last month, we already reported that Bioware would be making five PC games available for free, and that fan-favorite Mass Effect 2 could be among those – the publisher already offered the game for free on December 20 for a short period of time, although it didn’t appear to be a part of EA’s Origin on the House promotion. Share Tweet Submitlast_img read more

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Radiation Therapy Guidelines Keep Evolving

first_imgFeature | Radiation Therapy | March 02, 2016 | Jeff Zagoudis Radiation Therapy Guidelines Keep Evolving New technologies and techniques are clinically validated and starting to appear in guidelines for lung, prostate and breast cancer News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more Catalyst PT image courtesy of C-RAD News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. Related Content News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more News | Radiation Oncology | July 31, 2019 Laura Dawson, M.D., FASTRO, Chosen as ASTRO President-elect The members of the American Society for Radiation Oncology (ASTRO) elected four new officers to ASTRO’s Board of… read more Photo courtesy of CarestreamLike with many other aspects of healthcare, technology has been the driving force behind the evolution of radiation therapy. New advancements have given rise to new, more precise techniques for delivering maximum radiation dose to tumor volumes with minimum effect to surrounding tissue. While still in various stages of clinical testing, many of these new techniques are starting to make their way into clinical guidelines for treatment of various common cancers.The American Society for Radiation Oncology (ASTRO) and the National Comprehensive Cancer Network (NCCN) are the two main organizations that release guidelines for radiation therapy treatment, but they reach their recommendations in different fashions: ASTRO guidelines are evidence-based, accumulated from systematic literature review, while NCCN guidelines — which are released more frequently — are largely consensus-based. Lung Cancer ASTRO released an updated guideline for locally advanced non-small cell lung cancer (NSCLC) in May 2015, examining both definitive and adjuvant radiotherapy. The guideline for definitive radiotherapy assesses both dose fractionation and treatment timing, which can depend on whether radiotherapy is conducted alone or in combination with chemotherapy. Clinical evidence indicates that radiation therapy alone has been shown to be more effective than observation or chemotherapy in terms of overall survival. However, there was a documented increase in treatment-related side effects, including pneumonitis and esophagitis. As a result, the ASTRO guidelines suggest that definitive radiotherapy alone can be used for patients who may not be able to endure multimodality treatment.1The recommended dose for this treatment setting is 60 Gy, delivered in 2 Gy fractions. A retrospective study found no differences in local control or overall survival with hypofractionation versus conventional scheduling.1 An international study presented at the 2015 ASTRO meeting may indicate a solution to the toxicity problem. Comparing intensity-modulated radiation therapy (IMRT) to 3-D conformal radiation therapy (3-D CRT), researchers found that IMRT offered comparable results with lower toxicity rates. A survey found that patients who underwent IMRT were also more likely to complete consolidative chemotherapy, a crucial component of the current standard for lung cancer care.2 The recommended dose remains the same for concurrent chemoradiation therapy. The ASTRO guideline panel found no evidence that an increased dose at regular intervals or hyperfractionation improved clinical outcomes for concurrent chemoradiation.1As for the timing of radiation therapy, patients showed higher overall survival, local control and response rate — but also toxicity — with concurrent chemoradiation compared to a sequential approach. As a result, concurrent chemoradiation is currently considered the standard of care. Not all patients are able to tolerate concurrent chemoradiation, however, and recent studies suggest that hypofractionation — delivering the radiation dose in fewer treatment sessions — may be an effective option for these cases. “Historically, radiation oncology has not been able to perform these studies because of limitations in the technology for design and delivery of the radiation,” said Bruce Minsky, M.D., professor of radiation oncology at MD Anderson Cancer Center in Houston. “However, changes in the technology now allow us to use much more conformal fields to design therapies that are able to accomplish this.”A recent trial conducted at Stanford University and the University of Texas Southwestern (UTSW) tested the efficacy of hypofractionation with modern advanced planning and delivery technologies. Patients were administered a dose of 50-60 Gy over the course of 15 treatment sessions in three weeks; the current standard of care is 30-40 treatments for six to eight weeks. Final results indicated hypofractionated treatment was generally well-tolerated, even among the poorest-performing patients. The research team noted this also could lead to a potential treatment cost savings.3 ASTRO and NCCN guidelines disagree somewhat on the benefit of adjuvant radiotherapy in lung cancer cases. The latest ASTRO guidelines indicate that post-operative radiotherapy does not improve overall survival, but that it may improve local control compared to observation strategies. The guideline panel found no level 1 evidence to support an indication for neoadjuvant (pre-op) RT. NCCN, on the other hand, believes that pre-operative radiotherapy could be an option for patients with resectable stage IIIA lung cancer. They also found that post-op radiotherapy significantly improved survival for patients with clinical stage I or II lung cancer that has been upstaged surgically to N2 or above (cancer has spread to the lymph nodes and/or metastasized beyond the lungs). Some patients may not be eligible for surgery at all, or may be deemed high-risk for such an approach. For this group, stereotactic body radiotherapy (SBRT) may offer another option, according to Tim Kruser, M.D., assistant professor in the Department of Radiation Oncology at Northwestern University Feinberg School of Medicine. “Recent NCCN guidelines have highlighted the role of this technique for patients who are deemed at high risk for surgical complications for early-stage lung cancer,” he said. “Recent research also suggests SBRT may be an alternative to surgery for patients with early-stage lung cancer, regardless of surgical risk. I think this increased use will be reflected in future NCCN guidelines.” Prostate CancerThe current guidelines for radiation therapy in prostate cancer have been in place since 2013, with input from ASTRO and the American Urological Association (AUA). Prostatectomy has long been the first option for treatment, with radiation therapy employed to attempt to limit recurrence. The long-standing clinical question, according to the guideline, has been whether radiotherapy should be conducted adjuvantly before recurrence or as a salvage therapy after recurrence.Each argument has its merits. Using salvage radiotherapy avoids unnecessary irradiation of patients who never experience recurrence; however, waiting until the cancer has recurred could allow it to progress to metastasis, especially for high-risk patients. The ASTRO/AUA guidelines conclude that the existing literature cannot generally recommend in favor of one over another for several reasons:• Lack of randomization in clinical trials;• Difference in patient characteristics, radiotherapy protocols, failure definitions and follow-up durations; and• Use of older radiotherapy techniques (external beam radiotherapy), making it unclear whether newer techniques might improve outcomes significantly enough to make a difference. With this in mind, the ASTRO/AUA document does offer some guidance for each procedure. Under these auspices, adjuvant radiotherapy is indicated for patients with adverse pathological features following prostatectomy — including positive surgical margins, seminal vesicle invasion and extraprostatic extension — with no detectable prostate-specific antigen (PSA) recurrence. Salvage radiotherapy is indicated for patients with adverse pathological features who do demonstrate detectable PSA recurrence (but no evidence of distant metastatic disease). A phase 2 clinical trial published in the September/October issue of the ASTRO journal, Practical Radiation Oncology, examined the potential of image-guided IMRT post-prostatectomy.4 Currently, treatment plans are devised based on computed tomography (CT) scans of the organ or area in question, but imaging can only be performed so frequently in order to avoid giving too much extra radiation dose to the patient. Image-guided radiation therapy (IGRT), on the other hand, combines imaging and radiation delivery in one machine, “so we’re able to both track tumor movement as well as re-plan patients on a periodic basis while they’re being treated,” said Minsky. For this particular image-guided study, the research team was interested in treatment-related toxicities, health-related quality of life (HRQoL) factors and biochemical outcomes for 68 patients treated with image-guided intensity modulated radiation therapy (IG-IMRT). Fifty-three patients received salvage radiation therapy and 15 received adjuvant radiotherapy; all patients received a dose of 66 Gy in 33 fractions. Treatment was delivered with IMRT and daily cone beam computed tomography (CBCT) guidance, with routine follow-up every three to six months during the first five years. Reported toxicities did not exceed grade 2 under the National Cancer Institute’s Common Terminology Criteria for Adverse Events, and only transient impacts to genitourinary and sexual performance HRQoL factors were noted.4   Breast CancerAt present, radiation therapy is indicated in breast cancer treatment following mastectomy to remove cancerous tissue. In most cases, whole breast irradiation (WBI) is utilized, followed by a boost dose to the tumor bed. Treatment is typically delivered over a total of five to six weeks. This treatment path can be difficult for patients, however, both in terms of radiation dose received and time spent traveling to and from treatment sessions. Several alternatives have been explored in recent years, with treatment guidelines beginning to reflect these options. For this reason, breast cancer guidelines have been among the first to recommend hypofractionation. A study published in the December 2014 International Journal of Radiation Oncology — Biology — Physics found that hypofractionated whole-breast irradiation (HF-WBI) for early-stage breast cancer increased 17.4 percent from 2004 to 2011, with HF-WBI patients showing similar disease-free and overall survival rates to those treated with conventionally fractionated WBI.5 The 2014 guideline from ASTRO and the Society of Surgical Oncology for whole breast irradiation in stages I and II invasive breast cancer referenced two other large randomized clinical trials that illustrated comparable long-term efficacy and toxicity data for the shorter schedule, suggesting it is a viable alternative.6 Regardless of the dose or delivery schedule, whole breast irradiation can result in greater toxicity to surrounding healthy tissue. For patients who cannot or choose not to undergo this treatment, accelerated partial breast irradiation (APBI) offers a more targeted option, delivering the entire radiation dose directly to the tumor bed and sparing surrounding tissue. One particular APBI technique that has seen recent growth is brachytherapy, when radioactive seeds are implanted and release the radiation directly inside the tumor cavity. This method can be used as a boost for conventional WBI or as a standalone therapy, allowing treatment completion in one day. Research presented at the 2015 ASTRO meeting found APBI using multicatheter brachytherapy was as effective in local control, disease-free and overall survival rates. The phase III study included 1,184 patients aged 40 or older with early-stage breast cancer who had undergone breast-conserving surgery. Patients were randomized to 50 Gy WBI for seven weeks with a 10 Gy tumor bed boost, or APBI for five days. Prior studies had indicated APBI for patients in their 50s and 60s, but this was the first study to suggest it is appropriate for patients in their 40s.7 The current ASTRO guideline for APBI, published in 2009, says the treatment is suitable for patients 60 and above (provided they meet other criteria); patients 50-59 are deemed cautionary, and patients 49 or younger are deemed unsuitable for APBI. The NCCN follows similar age brackets, but prescribes a dose of34 Gy in 10 fractions delivered twice per day with brachytherapy. APBI with external beam radiation therapy has a prescribed dose of 38.5 Gy in 10 fractions, delivered twice daily.8  References1. Rodrigues, G., et al. “Definitive radiation therapy in locally advanced non-small cell lung cancer: Executive summary of an American Society for Radiation Oncology (ASTRO) evidence-based clinical practice guideline.” Practical Radiation Oncology, May 2015.  2. “IMRT for Lung Cancer Associated With Fewer Side Effects, Better Chemotherapy Tolerance.” www.itnonline.com, Oct. 28, 2015. 3. “Precision Hypofractionated Radiotherapy Effective in Locally Advanced Non-small Cell Lung Cancer.” www.itnonline.com,Jan. 26, 2016.4. “Post-prostatectomy Image-guided IMRT.” www.itnonline.com,Nov. 11, 2015. 5. “Use of Hypofractionated Whole-Breast Irradiation for Early-Stage Breast Cancer Patients Increasing.” www.itnonline.com, Dec. 16, 2014.6. Moran, Meena S., et al. “Society of Surgical Oncology – American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer.” International Journal of Radiation Oncology Biology Physics, March 2014. 7. “APBI With Multicatheter Brachytherapy Effective for Low-Risk Patients After Breast Conserving Surgery.” www.itnonline.com,Oct. 19, 2015.8. Smith, Benjamin D., et al. “Accelerated Partial Breast Irradiation Consensus Statement from the American Society for Radiation Oncology (ASTRO.” International Journal of Radiation Oncology Biology Physics, July 2009.  FacebookTwitterLinkedInPrint分享 News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more News | Proton Therapy | August 06, 2019 IBA Signs Contract to Install Proton Therapy Center in Kansas IBA (Ion Beam Applications S.A.) recently signed a contract and received the first payment for a Proteus One solution… read more News | Cardio-oncology | July 29, 2019 Statins Reduce Stroke, Cardiovascular Risk in Cancer Patients Following Radiation Cancer patients taking cholesterol-lowering statin medication following radiation therapy of the chest, neck or head… read more Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications News | Radiation Therapy | August 02, 2019 Varian Showcases Cancer Care Systems and Software at AAPM 2019 Varian showcased systems and software from its cancer care portfolio, including the Identify Guidance System, at the… read more Videos | Radiation Therapy | July 30, 2019 VIDEO: Use of Radiotherapy to Noninvasively Ablate Ventricular Tachycardia Pierre Qian, MBBS, read more Pierre Qian explains radiotherapy to ablate VTVideo Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 7:34Loaded: 2.19%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -7:34 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.last_img read more

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Related Sitting Comfortably finding the right a

first_img RelatedSitting Comfortably? – finding the right airline seatHad I discovered www.seatguru.com prior to my trip, I would have had a much more comfortable flight.Top 10 most badly behaved celebrities on flightsTop 10 most badly behaved celebrities on flightsFlying-themed films: 10 best plane movies of all timeWe celebrate Flight’s Oscar nomination by bringing you the 10 best films about flying and air travel, and stuff, of all time. Er, excuse me, I think you’ve dribbled on my shoulder…Got on the plane, bagged a window seat; avoided the puking baby at Gate 7; no hyperactive child behind you kicking you in the back: what could possibly go wrong? Well… your neighbour could fall asleep on you.Steve Cullum found himself in this awkward situation on recent domestic flight in the US when his middle seat neighbour, a middle-aged woman – who he described as ’very sleepy the minute she got on the plane’ – fell sound asleep, using his arm as a pillow.After failing to move his new intimate partner, Steve decided to film the situation. His struggle to extricate himself from this unfortunate position has become a YouTube smash.“This lady was totally out of it. As soon as she sat down, she started falling asleep, and it only got worse as the flight continued,” he explains. Unfortunately, due to turbulence, Steve couldn’t call on an air steward for assistance, and nothing he did seemed to shift her. You can watch his hilarious fight for freedom in the video below.Eventually the woman moves, only to turn her attentions to the guy in the aisle seat. Lucky man!More: 6 of the most annoying plane passengers – and how to beat themMore: 13 most annoying plane passengers: in cartoon form!ReturnOne wayMulti-cityFromAdd nearby airports ToAdd nearby airportsDepart14/08/2019Return21/08/2019Cabin Class & Travellers1 adult, EconomyDirect flights onlySearch flights Maplast_img read more

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